
Bio-Lab Automatic Tangential Flow Filtration System
The Bio-TFF Tangential Flow Filtering System is an easy-to-use automatic ultrafiltration UF/DF system designed for biopharmaceutical process development, pilot studies, and small-scale manufacturing. The Bio TFF system is designed in a unique and intelligent manner, which not only enhances process performance but also achieves an incredibly low minimum working volume, maximum ultrafiltration concentration multiple, and optimal product recovery function.
Technical–Features of Bio-Lab Automatic Tangential Flow Filtration System
01.
Hygienic design, in accordance with GMP and ASME BPE regulations;
02.
Use a sanitary-grade quaternary diaphragm or rotor pump with minimal shear force and pulse.
03.
Includes automatic TMP control, concentration, equal volume filtration, and other features.
04.
Includes a built-in integrity detection module, eliminating the requirement for an external detector.
05.
Our Chinese and English operating systems meet FDA 21 CFR Part 11 criteria.
06.
Customization can be tailored to specific customer needs.
07.
Provide complete GMP verification documentation and services.
Bio-Lab Automatic Tangential Flow Filtration System
| Model | Bio-TFF30 | Bio-TFF180 | Bio-TFF850 |
|---|---|---|---|
| Circulating pump flow rate | Peristaltic pump | Quaternary diaphragm pumps | |
| 0-2L/min | 0.7-180L/h | 50-850L/h | |
| Flow rate of the fluid replenishment pump | Peristaltic pump | ||
| The maximum flow rate: 2L/min | The maximum flow rate: 2L/min | The maximum flow rate: 3L/min | |
| Maximum system pressure | 4bar | 6bar | |
| Filter membrane area | 100cm² - 0.1㎡ | 0.1 - 0.5㎡ | 0.5 - 2.5㎡ |
| Weigh | Weighing range 6kg, reading accuracy 0.1g | Weighing range 10kg, reading accuracy 0.1g | |
| Circulation storage tank | PP material, available in 1000ml and 5000ml | ||
| Working Temperature Range | 2-40℃ | ||
| Pressure sensors | Inlet end*1, return end*1, through end*1; Detection range: 0-10bar | ||
| Control mode | Constant pressure, constant current, constant TMP, constant speed, constant weight automatic liquid replenishment, etc | ||
| Computer | Business computers of brands such as HP, Lenovo and Huawei, with memory ≥8G and hard disk ≥1T | ||
| Optional Configurations | Multi-Channel Selector Valves | Automatic switching of samples, replacement buffers, water, alkali, etc | |
| Conductivity detector | 0-999mS/cm accuracy ± 3% | Measuring range: 1μS/cm-100mS/cm, accuracy ±3%; 100-300mS/cm accuracy ±5% (25℃) | |
| Membrane wrapping fixture | Can be clamped 0.1m² ×5 and 0.5m² ×5 Membrane wrapping fixture | ||
| Flowmeter | Multiple brands to choose from, ultrasonic flowmeter | ||
| pH Detector | Detection range: 0-14, accuracy ±0.1 | ||
Frequently Asked Questions
The Bio-Lab Automatic Tangential Flow Filtration System is an innovative filtration system specifically built for biopharmaceutical research and development. It provides effective ultrafiltration (UF/DF) of antibodies, vaccines, and nucleic acid medicines, resulting in excellent recovery, precision, and consistency in small-scale production.
The tangential flow filtering system improves the biopharmaceutical process by automating essential steps like concentration, diafiltration, and collection. With TMP control and real-time data recording, this filtration equipment assures repeatability, process stability, and maximum product yield.
The Bio-Lab filtering system is constructed in accordance with GMP and ASME BPE requirements. Its hygienic design, low-shear sanitary-grade pump, and FDA 21 CFR Part 11-compliant software offer superior quality, dependability, and traceability in any biopharmaceutical application.
Yes, the Bio-Lab tangential flow filtration system can be combined with a conditioning system for more efficient buffer management and process control. This link improves filtration precision, streamlines operation, and enables automated data synchronization in biopharma workflows.
Intech's filtering equipment is automated, flexible, and compliant with international standards. The Bio-Lab tangential flow filtration system requires minimal user intervention, low maintenance, and complete GMP certification, making it perfect for efficient and compliance biopharmaceutical manufacturing.
Contact Intech Analytical Instruments
Office Address
Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500085
Lab Address
Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043



