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Bio-Lab Automatic Tangential Flow Filtration System

The Bio-TFF Tangential Flow Filtering System is an easy-to-use automatic ultrafiltration UF/DF system designed for biopharmaceutical process development, pilot studies, and small-scale manufacturing. The Bio TFF system is designed in a unique and intelligent manner, which not only enhances process performance but also achieves an incredibly low minimum working volume, maximum ultrafiltration concentration multiple, and optimal product recovery function.

Technical–Features of Bio-Lab Automatic Tangential Flow Filtration System

01.

Hygienic design, in accordance with GMP and ASME BPE regulations;

02.

Use a sanitary-grade quaternary diaphragm or rotor pump with minimal shear force and pulse.

03.

Includes automatic TMP control, concentration, equal volume filtration, and other features.

04.

Includes a built-in integrity detection module, eliminating the requirement for an external detector.

05.

Our Chinese and English operating systems meet FDA 21 CFR Part 11 criteria.

06.

Customization can be tailored to specific customer needs.

07.

Provide complete GMP verification documentation and services.

Bio-Lab TFF System Table
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Bio-Lab Automatic Tangential Flow Filtration System

Model Bio-TFF30 Bio-TFF180 Bio-TFF850
Circulating pump flow rate Peristaltic pump Quaternary diaphragm pumps
0-2L/min 0.7-180L/h 50-850L/h
Flow rate of the fluid replenishment pump Peristaltic pump
The maximum flow rate: 2L/min The maximum flow rate: 2L/min The maximum flow rate: 3L/min
Maximum system pressure 4bar 6bar
Filter membrane area 100cm² - 0.1㎡ 0.1 - 0.5㎡ 0.5 - 2.5㎡
Weigh Weighing range 6kg, reading accuracy 0.1g Weighing range 10kg, reading accuracy 0.1g
Circulation storage tank PP material, available in 1000ml and 5000ml
Working Temperature Range 2-40℃
Pressure sensors Inlet end*1, return end*1, through end*1; Detection range: 0-10bar
Control mode Constant pressure, constant current, constant TMP, constant speed, constant weight automatic liquid replenishment, etc
Computer Business computers of brands such as HP, Lenovo and Huawei, with memory ≥8G and hard disk ≥1T
Optional Configurations Multi-Channel Selector Valves Automatic switching of samples, replacement buffers, water, alkali, etc
Conductivity detector 0-999mS/cm accuracy ± 3% Measuring range: 1μS/cm-100mS/cm, accuracy ±3%; 100-300mS/cm accuracy ±5% (25℃)
Membrane wrapping fixture Can be clamped 0.1m² ×5 and 0.5m² ×5 Membrane wrapping fixture
Flowmeter Multiple brands to choose from, ultrasonic flowmeter
pH Detector Detection range: 0-14, accuracy ±0.1

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Frequently Asked Questions

The Bio-Lab Automatic Tangential Flow Filtration System is an innovative filtration system specifically built for biopharmaceutical research and development. It provides effective ultrafiltration (UF/DF) of antibodies, vaccines, and nucleic acid medicines, resulting in excellent recovery, precision, and consistency in small-scale production.

Contact Intech Analytical Instruments

Office Address

Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500085

Lab Address

Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043

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