
Oligonucleotide Synthesis Column
Intech-Hanbon offers a complete line of BioOligo synthesizer machines and nucleic acid synthesis columns for laboratory, pilot, and production-scale applications. These BioOligo systems are precisely engineered to provide effective oligonucleotide synthesis, purification, and scalability from research to commercial manufacturing. Intech-Hanbon’s BioOligo series is integrated with advanced liquid chromatography systems and compatible with high performance liquid chromatography (HPLC) and preparative chromatography setups. It offers exceptional accuracy, reliability, and compliance with global quality standards, making it ideal for biotechnology, pharmaceutical, and genomic research applications.
Oligonucleotide Synthesis Column
Features of small synthesis columns
1. 316L stainless steel;
2. Specifications 6.3ml, 12ml, 24ml and 48ml are available;
3. Material of synthetic column combines biocompatibility and harsh organic conditions;
Model NO.
Volume
Inner diameter (ID)
Column height
SYC 6.3
6.3ml
20mm
20mm
SYC 12
12ml
27mm
21mm
SYC 24
24ml
35mm
25mm
SYC 48
48ml
44mm
32mm
Features of medium-sized synthesis columns
1. The inner diameter of the column cylinder is 35mm, and the volume range is 10ml-144ml;
2. The height of the column bed is adjustable, which is convenient and flexible. It is recommended that the working height be 5cm-8cm
Model NO.
Volume
Column height
SYC 25
25mm
150mm
SYC 35
35mm
150mm
SYC 52
52mm
135mm
Features of Pilot-Scale Nucleic Acid Synthesis columns:
1. The specifications of the synthesis column include ID60mm, ID70mm, ID140mm, ID150mm and ID200mm, with a maximum pressure resistance of 2MPa.
2. The synthesis column is equipped with a distributor to ensure uniform distribution of the solution on the sieve plate.
3. The synthesis column is resistant to acetonitrile, toluene, and dichloroacetic acid or trichloroacetic acid of certain concentrations.
Model NO.
Inner diameter (ID)
Column height
Oligo-MCC 60
60mm
80mm
Oligo-MCC 70
70mm
225mm
Oligo-MCC 140
140mm
260mm
Oligo-MCC 150
150mm
260mm
Oligo-MCC 200
200mm
260mm
Features of production oligonucleotide synthesis columns:
1. The specifications of the synthesis column include ID300mm, ID350mm, ID400mm, ID450mm and ID600mm, with a maximum pressure resistance of 2MPa.
2. The synthesis column is equipped with a distributor to ensure uniform distribution of the solution on the sieve plate.
3. The synthesis column is resistant to acetonitrile, toluene, and dichloroacetic acid or trichloroacetic acid of certain concentrations.
Model NO.
Inner diameter (ID)
Column height
Oligo-MCC 300
300mm
260mm
Oligo-MCC 350
350mm
260mm
Oligo-MCC 400
400mm
260mm
Oligo-MCC 450
450mm
260mm
Oligo-MCC 300
600mm
260mm
Frequently Asked Questions
For any operational scale, including laboratory research, pilot-scale trials, and full production, Intech-Hanbon provides a comprehensive selection of oligonucleotide synthe columns and nucleic acid synthesis columns. Their robust 316L stainless-steel design and adaptable specs guarantee dependable performance in any setting.
Intech-Hanbon offers small nucleic acid synthesis columns in capacities of 6.3 ml, 12 ml, 24 ml, and 48 ml. These columns are constructed from 316L stainless steel. These columns are perfect for high-precision synthesis in laboratory settings because they combine biocompatibility with resistance to strong organic solvents.
Because of its changeable bed height, medium-scale oligo synthesis columns make it simple for customers to alter operating conditions to suit various synthesis needs. These columns are ideal for pilot testing and process optimization because of their 35 mm inner diameter and volume range of 10 ml to 144 ml.
The pilot-scale nucleic acid synthesis columns can tolerate pressures of up to 2 MPa and come with inner diameters that range from 60 mm to 200 mm. In addition to being resistant to acetonitrile, toluene, and dichloroacetic acid, each column has a distributor system to guarantee uniform reagent delivery and longevity in demanding applications.
Indeed, Intech-Hanbon's production-scale oligonucleotide synthesis columns are designed for synthesis at the industrial level. These columns provide reliable, large-scale nucleic acid production with great efficiency thanks to its uniform distribution system, 2 MPa pressure resistance, and diameters up to 600 mm.
Contact Intech Analytical Instruments
Office Address
Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500072
Lab Address
Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043



