Bio-Oligo Laboratory Nucleic Acid Synthesis Instrument
The Bio-Oligo Laboratory Nucleic Acid Synthesis Instrument is available in three scalable models to meet diverse synthesis requirements. The Bio-Oligo 100 can handle 50 μmol to 9 mmol, the Bio-Oligo 10 is suitable for synthesis in the 10 μmol to 50 μmol range, and the Bio-Oligo 150 is made for higher-volume applications. The system’s modular design and clever software enable flexible DNA/RNA synthesis using interchangeable synthesis columns with different capacities. These tools guarantee accuracy and versatility in laboratory operations and are perfectly suited for clinical research, nucleic acid drug discovery, and the creation of molecular diagnostic probes.
Technical Features of Bio-Oligo 100 Nucleic Acid/DNA Synthesizer Machine
01.
Biocompatibility
Incorporates a stacked piping configuration with minimal dead volume, designed to withstand conventional organic solvents such as acetonitrile and toluene, as well as dichloroacetic acid (3–10%) and other reactive reagents.
02.
Precision Flow Control
Dual PEEK pump heads ensure exceptional flow accuracy within ±1%, with repeatability maintained at RSD ≤ 0.5%. A built-in self-cleaning mechanism enhances durability and operational stability.
03.
Intelligent User Management
A modular framework simplifies maintenance while supporting secure multi-user access, data tracking, and complete information security.
04.
Flexible Method Programming
Customizable process parameters and editable synthesis protocols, paired with an intuitive interface, deliver a seamless human–machine interaction experience.
05.
Advanced Automation
Optimized for minimal reagent consumption, the system continuously monitors synthesis pressure, conductivity, and UV detection, enabling precise, automated process control.
06.
High synthesis efficiency
Capable of cycle times ranging from 4.5 to 25 minutes for standard DNA, achieving synthesis efficiencies exceeding 99% for DNA and 98% for RNA, across variable sequence lengths.
07.
Configurable Monomer Capacity
Expandable monomer bottle storage of up to 18 units, supporting advanced requirements such as the synthesis of modified or specialty monomers.
08.
Regulatory Alignment
Software developed in full compliance with international regulatory standards, including 21 CFR Part 11, ensuring traceability and validation for clinical and industrial applications.
Bio-Oligo Synthesis
Parameter Configuration（Bio-Oligo 150)
Power supply
220V±5% AC
Power
1200W
Weight
55kg
External dimensions
652×585×622mm
Working temperature
10-40℃
Relative humidity
＜30%
Synthetic scale
50μmol-12mmol
Solvent compatibility
Deprotection reagents, BTT, thiosulfate reagents, etc
Column reactor
1个
Base bottle mouth
can be expanded to 15 units. Customization is also available
Single cycle time
＜30min
Synthetic efficiency
＞99% for DNA ＞98% for RNA
Related Products
Bio-Oligo Pro 400 Nucleic Acid Synthesizer
Bio Oligo Pro Series Production Grade Nucleic Acids
Oligonucleotide Synthesis Column
Frequently Asked Questions
Contact Intech Analytical Instruments
Office Address
Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500085
Lab Address
Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043